Improving Muscular Performance & Endurance
Many athletes and people in sports look for ways to improve their muscle strength, endurance; their performance indicators.
Read below to find out Dr. Gutman’s comments and dive in into the Abstract of the study to see their findings.
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Dr. Gutman’s Comments:
Dr. Larry Lands of McGill University conceived this study after hearing repeated reports of improved performance by athletes taking Immunocal. As a scientist, he sought evidence to validate these claims. Young athletic adults were given either a placebo or Immunocal. All underwent the same physical training program. Three months later, when measured for muscle strength and endurance, their performance indicators (strength and endurance) had improved by 10-15%—a substantial advantage in competitive sports. At the same time, glutathione levels in this healthy population climbed a significant 35%. Subsequent studies on muscular performance and Immunocal have since reinforced these results.
The Effect of Supplementation with a Cysteine Donor on Muscular Performance
Abstract
Oxidative stress contributes to muscular fatigue. Glutathione (GSH) is the major intracellular antioxidant, whose biosynthesis is dependent upon cysteine availability. We hypothesized that supplementation with a whey-based cysteine donor (Immunocal (HMS90)) designed to augment intracellular GSH, would enhance performance. Twenty healthy young adults (10 m) were studied pre- and 3 months post-supplementation with either Immunocal (20 gm/day) or casein placebo. Muscular performance was assessed by whole leg isokinetic cycle testing, measuring Peak Power and 30-sec Work Capacity. Lymphocyte GSH was used as a marker of tissue GSH. There were no baseline differences (age, ht, wt, % ideal wt, Peak Power, 30-sec Work Capacity). Followup data on 18 subjects (9 Immunocal, 9 placebo) were analyzed. Both peak power [13 +/- 3.5 (SE) %, P < 0.02] and 30-s work capacity (13 +/- 3.7%, P < 0.03) increased significantly in the Immunocal group, with no change (2 +/- 9.0 and 1 +/- 9.3%) in the placebo group. Lymphocyte GSH also increased significantly in the Immunocal group (35.5 +/- 11.04%, P < 0.02), with no change in the placebo group (-0.9 +/- 9.6%). This is the first study to demonstrate that prolonged supplementation with a product designed to augment antioxidant defenses resulted in improved volitional performance.
From the JOURNAL OF APPLIED PHYSIOLOGY, 87: 1381-1385, 1999
LC Lands, MD, PhD*†, VL Grey, PhD†‡, AA - Smountas, BSc* *Division of Respiratory Medicine, † Department of Pediatrics, ‡Department of Biochemistry, McGill University Health Centre-Montreal Children’s Hospital, Montreal, Quebec, Canada
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